发明名称 |
7-ALKYL STEROID DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE IN MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
摘要 |
Novel 7-alkyl- DELTA 4-17 alpha -pregnene-3-ones of the formula <IMAGE> I wherein R is selected from the group consisting of saturated and unsaturated alkyl of 2 to 8 carbon atoms, cycloalkyl alkyl of 4 to 8 carbon atoms and arylalkyl of 7 to 12 carbon atoms and X and Y form the group <IMAGE> or X is OH and Y is <IMAGE> and M is selected from the group consisting of hydrogen, alkali metal and NH4 and the wavy line indicates the alpha - or beta -position or mixtures thereof having aldosterone antagonistic activity and increased hydrosodium diuresis with organic potassium conservation while devoid of secondary hormonal effects and their preparation. |
申请公布号 |
DE3060488(D1) |
申请公布日期 |
1982.07.22 |
申请号 |
DE19803060488 |
申请日期 |
1980.03.13 |
申请人 |
ROUSSEL-UCLAF |
发明人 |
NEDELEC, LUCIEN;TORELLI, VESPERTO;FOURNEX, ROBERT;TOURNEMINE, COLETTE |
分类号 |
A61K31/565;A61K31/575;A61K31/585;A61P5/38;A61P9/00;A61P9/12;C07J1/00;C07J9/00;C07J21/00;C07J51/00;(IPC1-7):C07J21/00;A61K31/56;A61K31/58 |
主分类号 |
A61K31/565 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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