| 发明名称 |
1-Alpha-hydroxy-vitamin=D prepn. - by allylic oxidn. of 5,6-trans-vitamin=D followed by irradiation |
| 摘要 |
<p>1-Alpha-hydroxylated vitamin D cpds. (I) are prepd. by allylic oxidn. of 5,6-trans-vitamin D, followed by exposing the oxidation prods. to actinic radiation in the presence of a photosensitising agent. (I) are used for treatment of calcium metabolism disorders. The process gives (I) in yields of 20-30%, which is higher than prior processes.</p> |
| 申请公布号 |
DE3048698(A1) |
申请公布日期 |
1982.07.15 |
| 申请号 |
DE19803048698 |
申请日期 |
1980.12.23 |
| 申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
E. PAAREN,HERBERT;F. DELUCA,HECTOR;K. SCHNOES,HEINRICH;E. HAMER,DAVID |
| 分类号 |
C07C401/00;(IPC1-7):07C172/00 |
主分类号 |
C07C401/00 |
| 代理机构 |
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代理人 |
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