| 摘要 |
<p>Compounds of the formula (IV): <CHEM> or acid addition salts thereof, wherein one of the groups R<5> is a group O(CH2)nYR<7> wherein Y is an oxygen or sulphur atom or a methylene, OCH2 or SCH2 group, n is an integer from 1 to 5 and R<7> is an optionally substituted phenyl group; the other group R<5> and R<6> being the same or different, each being hydrogen, halogen, C2-4alkenyl, C2-4alkenyloxy, nitro, cyano, hydroxy, benzyloxy, C1-4alkyl or C1-4alkoxy, the alkyl or alkoxy group being substituted by halogen, hydroxy, or C1-2alkoxy; amino optionally substituted by one or two C1-4alkyl or C1-4acyl groups or the nitrogen atom forming part of a five or six membered heterocyclic ring, a group -OSO2R<8> or S(O)rR<8> wherein R<8> is C1-3alkyl and r is 0,1 or 2 a group -COR<9> wherein R<9> is methyl, ethyl, methoxy, ethoxy, amino, methylamino, ethylamino, dimethylamino or diethylamino, are useful for the treatment of bacterial infections. A process for preparing these compounds and novel chemical intermediates used in their preparation are disclosed as is the first medical use of the compounds of the formula (IV) and pharmaceutical compositions containing them.</p> |
