| 摘要 |
<p>TRIAZOLYLBENZOPHENONE DERIVATIVES AND PRODUCTION THEREOF: Triazolylbenzophenone derivatives of the formula: (wherein R represents hydrogen, C1-C6 alkyl, C1-C6 halo-alkyl, the group -(CH2)n-X-R5,or the group ; R5 represents hydrogen, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C6 C10 aryl, or C2-C8 acyl; X represents sulfur or oxygen; n represents 0, 1, 2, or 3; R6 and R7 each represents hydrogen or C1-C6alkyl: or the group R6-?-R7 represents pyrrolidino, piperidino, morpholino, or .gamma.-methylpiperazino; R1 represents hydrogen or halogen; R2 represents halogen, nitro, or trifluoromethyl; R3 represents C1-C6 alkyl, C1 C6 halo-alkyl, C1-C6 azido-alkyl, C6-C10 aryl, C2-C8 acyl or the group ; R4 and R8 each represents hydrogen, C1-C6 alkyl, or C7-C10 aralkyl; R9 represents hydrogen or C1-C6 alkyl; R10 represents hydrogen, C1-C6 alkyl, C7-C10 aralkyl, or C2-C11 .alpha.-amino-acyl; or the group R9-?-R10 represents phthalimido, pyrrolidino, piperidino, morpholino, or .gamma.-methylpiperazino) and their pharmaceutically acceptable acid addition salts, being useful as anxiolytics, sedatives, hypnotics, anticonvulsants, muscle relaxants, antidepressants,or their synthetic intermediates, are prepared.</p> |
