摘要 |
<p>Compounds of the formula <IMAGE> wherein R1 is hydrogen, halogen or cyano; R2 is fluorine, cyano, trifluoromethyl, nitro or alkyl of 1 to 4 carbon atoms; R3 is alkoxy of 1 to 5 carbon atoms, alkenyloxy of 2 to 5 carbon atoms, aryloxy of 6 to 10 carbon atoms, aralkoxy of 7 to 11 carbon atoms, or -NR5R6, where R5 and R6 are each hydrogen, alkyl of 1 to 5 carbon atoms, alkenyl of 2 to 5 carbon atoms, aryl of 6 to 10 carbon atoms or aralkyl of 7 to 11 carbon atoms; and R4 is cycloalkyl of 3 to 5 carbon atoms or alkyl of 3 to 5 carbon atoms; and non-toxic, pharmacologically acceptable acid addition salt thereof. The compounds as well as the salts are useful as analgesics, uterospasmolytics and antiasthmatics.</p> |
申请人 |
THOMAE KARL DR GMBH, 7950 BIBERACH |
发明人 |
ENGELHARDI,GUENTHER;KECK,JOHANNES;KRUEGER,GERD;NOLL, KLAUS;PIEPER,HELMUT |