Method of using 4-anilinoquinazoline derivatives as analgesic and anti-inflammatory agents

摘要

A method of using 4-anilinoquinazoline derivatives of formula (I): <IMAGE> (I) (in which: R1 represents a hydrogen atom, a halogen, atom, a trifluoromethyl group or a nitro group; R2 represents a hydrogen atom, a C1-C4 alkyl group, an alkoxy group or a halogen atom; and R3 represents a hydrogen atom or a C1-C4 alkyl group) and pharmaceutically acceptable salts thereof are, provided that R1 does not represents a hydrogen atom or a chlorine atom in the 6- position when R2 and R3 both represent hydrogen atoms, as an analgesic and anti-inflammatory in the treatment of mammals. These compounds can be prepared by heating the appropriate 4-haloquinazoline with an appropriate aniline or aniline derivative.