| 摘要 |
<p>PURPOSE:To prepare the titled hormone in a large quantity at a low cost, by transplanting cells, having the ability to produce the titled hormone, and derived from a main to a nonhuman warm-blooded animal body, and reacting the resultant cells with an inducer for the titled hormone. CONSTITUTION:Cells having the ability to produce a human luteinizing hormone, e.g. basophilic cells or tumorous basophilic cells of the anterior lobe of the human hypophysis, are transplanted to a warm-blooded animal body, e.g. a bird, dog, horse, rat, hamster or nude mouse, and multiplied. Alternatively, the cells derived from a man are multiplied in a chamber while supplying a body fluid containing a nutrient from the animal body to the chamber. The resultant cells are then reacted with an inducer for the luteinizing hormone, e.g. lysine, leucine or potassium chloride, salted out, centrifuged and concentrated to purify and separate the luteinizing hormone, which is then collected.</p> |
