摘要 |
Spiro-quinolone hydantoins having utility in preventing or alleviating chronic diabetic complications such as cataracts, reinopathy and neuropathy of the formula:
<CHEM>
and the pharmaceutically acceptable acid addition salts thereof, wherein n is 1 or 2 and R1 and R2 are each hydrogen, chloro, bromo, fluoro, C1-C3 alkyl or C1-C3 alkoxy; pharmaceutical composition containing them, and processes for their preparation. |