发明名称 IMMUNOLOGICALLY ACTIVE DIPEPTIDYL-5-0, 6-0-ACYL-2-AMINO-2-DEOXY-D-GLUCOFURANOSE DERIVATIVE AND MANUFACTURE
摘要 Immunologically active compounds of the formula: <IMAGE> (I.) hydrogen; C1-30 alkyl; C2-30 alkenyl; C1-30 alkoxy; phenyl; C1-20 alkylsulfonyl; or cholesteryl; and R4 may additionally be hydrogen; R5 is hydrogen; or R5-R6 together is -CH2-CH2-CH2; R6 is hydrogen; C1-7 alkyl; hydroxymethyl; mercapto-methyl; benzyl; or substituted benzyl; R7 and R8 may be the same or different and are each independently COOR or CONR'R'', where R is hydrogen or C1-7 alkyl, and R' and R'' are each independently hydrogen or C1-3 alkyl; when R2 is C1-10 alkyl, the stereochemistry at asymmetric center I can be either D or L; when R6 is not hydrogen, the stereochemistry at asymmetric center Ii is L; the stereochemistry at asymmetric center III is D.
申请公布号 JPS56169697(A) 申请公布日期 1981.12.26
申请号 JP19810067075 申请日期 1981.05.06
申请人 MERCK & CO INC 发明人 FUIRITSUPU ERU DEYURETSUTO
分类号 A61K39/39;C07J17/00;C07K9/00 主分类号 A61K39/39
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