| 摘要 |
PURPOSE:To obtain the subject compound useful as an intermediate for agricul tural chemicals and medicines in good yield by rearranging a propargyl alcohol compound in the presence of a perrhenate and an arylsulfonic acid. CONSTITUTION:A compound expressed by formula I (R1 is lower alkyl, phenyl- substituted alkyl or phenyl; R2 is H or lower alkyl; R3 is H, phenyl or trimethylsilyl) is rearranged in the presence of a perrhenate (e.g. tetrabutylammonium perrhenate) and an arylsulfonic acid (e.g. p-toluenesulfonic acid) in a solvent such as dichloromethane at ordinary temperature or, as necessary, by heating and stirring the reactional mixture to afford a compound expressed by formula II. As the objective compound expressed by formula I.1-Phenyl-1-propane-1-yn-1-ol is exemplified as the compound. |
