发明名称 |
HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE IN TYROSINEKINASE INHIBITION |
摘要 |
Heterocyclic compounds represented by general formula (I) wherein R stands for an optionally substituted aromatic heterocyclic group; X stands for oxygen atom, an optionally oxidated sulfur atom, -C(=O)- or -CH(OH)-; Y stands for CH or N; m denotes an integer of 0 to 10; n denotes an integer of 1 to 5; cyclic group -NB) stands for an optionally substituted aromatic azole group; and ring A is optionally further substituted, or salts thereof. The compound (I) possesses action of inhibiting tyrosine kinase and useful as antitumor agents.
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申请公布号 |
CA2260999(A1) |
申请公布日期 |
1998.01.29 |
申请号 |
CA19972260999 |
申请日期 |
1997.07.17 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
MOMOSE, YU;MATSUTANI, ETSUYA |
分类号 |
C07D413/12;C07D521/00;(IPC1-7):C07D413/12;C07D473/00;C07D475/00;C07D471/04;C07D487/04;C07D401/12;C07D403/12;C07D409/12;C07D411/12;C07D417/12;C07D405/14;C07D409/14;C07D413/14;C07D417/14;A61K31/42;A61K31/425;A61K31/435;A61K31/495;A61K31/53;A61K31/535;A61K31/54 |
主分类号 |
C07D413/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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