摘要 |
Compositions and methods for the treatment of anorectal disorders are provided in which certain combinations of NO donors, PDE inhibitors, superoxide (O2-) scavengers, beta-adrenergic agonists, cAMP-dependent protein kinase activators, alpha1- adrenergic antagonists, L-type Ca2+ channel blockers, estrogens, ATP-sensitive + channel activators and smooth muscle relaxants are used.
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