| 摘要 |
Imidazole derivatives of the formula <IMAGE> I wherein X is hydrogen or C1-4-alkyl, Y is sulfur, sulfinyl or sulfonyl and Z is thienyl, optionally substituted by methyl or fluorine, or a group of the formula <IMAGE> Z wherein R1, R2 and R3 are hydrogen, methyl, fluorine, hydroxy, methoxy, methylthio or two of R1, R2 and R3 on adjacent carbon atoms taken together are methylenedioxy or ethylenedioxy or one of R1, R2 and R3 is mono- or di-(C1-4-alkyl)-amino and the other two are hydrogen, and physiologically or pharmaceutically compatible or acceptable acid addition salts thereof, are described. The compounds of formula I inhibit the aggregation of the blood platelets and have antihyperglycemic activity. |
