| 摘要 |
The invention provides new derivatives of vitamin D3, specifically, 1 alpha -hydroxy-2 beta -fluorocholecalciferol. The compound is characterized by vitamin D-like activity as measured by its ability to stimulate intestinal calcium transport, mobilize calcium from bone, increase serum inorganic phosphorous and in their antirachitic acitivity. The compound could, therefore, find ready application as a substitute for vitamin D in its various known applications and in the treatment of various metabolic bone diseases. |
