MUCOPOLYSACCHARIDES HAVING BIOLOGICAL PROPERTIES,PREPARATION AND APPLICATION THEREOF AS DRUGS

摘要

Mucopolysaccharides biologically active and more specific than heparin, particularly with respect to the blood factor Xa. These mucopolysaccharides may be obtained by partial depolymerisation, under heparin conditions by the action of a chemical agent such as nitrous acid. The conditions implemented allow the preparation of mucopolysaccharides having a USP titre lower than that of the starting heparin and a Yin-Wessler titre at least equal to that of said heparin. These products may be used particularly as antithrombotic drugs.