发明名称 |
PREPARATION OF GAMMA-PYRONES FROM 3-SUBSTITUTED FURANS |
摘要 |
<p>Gamma-pyrones are prepared by contacting a 3-halo-furfuryl alcohol or a 3-alkoxy-furfuryl alcohol with one equivalent of a halogen, peracid or peroxide oxidant and then heating until hydrolysis of the formed 4-substituted-dihydropyran intermediate is substantially complete. Maltol (2-methyl-3-hydroxy-4H-pyran-4-one) is prepared by this process from 2-(1-hydroxyethyl)-3-alkoxy furans or 2-(1-hydroxyethyl)-3-halo-furans. Gamma-pyrones are also prepared by contacting the corresponding 3-substituted-2,5-dialkoxy-furfuryl alcohols with acid until conversion to the gamma-pyrones is substantially complete.</p> |
申请公布号 |
CA1109478(A) |
申请公布日期 |
1981.09.22 |
申请号 |
CA19770290679 |
申请日期 |
1977.11.10 |
申请人 |
PFIZER INC. |
发明人 |
BRENNAN, THOMAS M.;BRANNEGAN, DANIEL P.;WEEKS, PAUL D.;KUHLA, DONALD E. |
分类号 |
C07D309/32;C07D309/40;(IPC1-7):07D309/40 |
主分类号 |
C07D309/32 |
代理机构 |
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