发明名称 Xanthine derivatives
摘要 Compounds of general formula <IMAGE> (I) wherein one of the groups R1 and R3 is a straight-chain or branched oxoalkyl group consisting from 5 to 8 carbon atoms and the oxygen atom is attached to a non-terminal carbon atom and is separated from the nearest ring nitrogen atom by at least 3 carbon atoms in ( omega -1)-oxoalkyl groups and by at least 4 carbon atoms in oxoalkyl groups in which the oxygen atom is separated from the terminal carbon atom by more than one carbon atom, R2 and the other one of groups R1 and R3 are straight chain or branched alkyl groups containing from 1 to 12 carbon atoms but wherein that group R1 or R3 which is other than an oxoalkyl group may also be hydrogen, one nitrogen-bound substituent being hydrogen or alkyl containing more than 1 carbon atom, and physiologically acceptable acid addition salts thereof, a process for their preparation and pharmaceutical compositions containing said compounds.
申请公布号 US4289776(A) 申请公布日期 1981.09.15
申请号 US19790032536 申请日期 1979.04.23
申请人 HOECHST AKTIENGESELLSCHAFT 发明人 MOHLER, WERNER;JAYME, MANFRED;KOMAREK, JAROMIR
分类号 A61K31/52;A61K31/522;A61P7/02;A61P9/08;C07D473/06;(IPC1-7):A61K31/52 主分类号 A61K31/52
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