Aromatic aminoethanol compounds and salts thereof, pharmaceutical compositions comprising them and processes for their production.

摘要

The invention provides compounds of the formula
<CHEM>
wherein A represents a direct bond or the group -O-CH2-, B represents a C1-C11 alkylene group bonded to a carbon atom of the aromatic ring D either directly or through -O-, -S-, -SO- or -NH-,
W represents a carbon or nitrogen atom, R1 represents a C1-C7 alkyl group, a hydroxy-C1-C6 alkyl group, or a phenyl- or diphenyl- alkyl group with the alkyl group having 1 to 4 carbon atoms,
R2 represents hydrogen, halogen, OH, C1-C4 alkyl, NO2, C1-C4 alkoxy, acetyl, allyloxy, carbamoyl or sulfamoyl, and when two or more R2 groups exist, they may be idential or different, and
n represents 1, 2 or 3 and m represents 1 or 2, provided that n + m >/= 4;
and acid addition salts thereof; processes for producing them; and pharmaceutical compositions comprising them for use in the treatment of diseases of the cardiovascular system.