发明名称 WERKWIJZE VOOR HET BEREIDEN VAN ANOREXISCH WERKZAME PREPARATEN; DE ONDER TOEPASSING DAARVAN VERKREGEN GE- VORMDE VOORTBRENGSELEN, ALSMEDE WERKWIJZE TER BEREIDING VAN ANOREXISCH WERKZAME VERBINDINGEN.
摘要 Novel piperazinylpyrazines of the formula <IMAGE> in which the substituents are defined in Claim 1, and their N-oxides are prepared. These compounds are obtained by reacting an appropriate pyrazine or its N-oxide, which contains an easily removable group in the 2-position, which is defined in Claim 1, with an appropriate piperazine. The compounds III are also prepared as acid addition salts. The compounds obtained can be used in pharmaceutical compositions having anorexic action.
申请公布号 NL167692(B) 申请公布日期 1981.08.17
申请号 NL19760003800 申请日期 1976.04.09
申请人 MERCK & CO., INC. TE RAHWAY, NEW JERSEY, VER. ST. V. AM. 发明人
分类号 C07D403/04;A61K31/495;A61P3/04;C07D241/20;C07D241/24;C07D241/26 主分类号 C07D403/04
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