Thiazolidine derivatives and their production and medicinal compositions containing them.

摘要

A thiazolidine derivatives of the formula:
<Chemistry id="chema01" num="0001"><Image id="ia01" he="28" wi="31" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein R is a phenyl group having 2 nuclear substituent groups selected from the class consisting of a lower alkyl having 1 to 6 carbon atoms, a lower alkoxy having 1 to 7 carbon atoms, hydroxyl and a carboxylic acyloxy having 1 to4 carbon atoms or a phenyl group having a methylenedioxy group in adjacent positions on its ring; R' is H or an alkyl having 1 to 6 carbon atoms, or a physiologically acceptable salt thereof is a novel compound and is having the activity to control certain chronic symptoms due to diabetes, such as diabetic cataract, diabetic neuropathy and diabetic retinosis.