发明名称 Antidiabetic furancarboxylic and thiphenecarboxylic acids
摘要 Compounds of the structure <IMAGE> wherein Z is oxygen or sulfur; R is (C1-C2)alkoxy; phenoxy; benzyl; phenylthiomethyl; phenylthio; phenylthio monosubstituted in the 2-, 3- or 4-position with (C1-C3)alkyl, phenyl, methoxy, chloro, fluoro or trifluoromethyl; phenylthio disubstituted in the 2,5- or 3,5- positions with methyl, methoxy, chloro, or fluoro; 2,3,5,6-tetrafluorophenylthio; 1- or 2-naphthylthio; (C2-C6)alkylthio; or halo (bromo or chloro); and the pharmaceutically-acceptable salts thereof are useful in lowering the blood glucose levels of hyperglycemic mammals.
申请公布号 US4282246(A) 申请公布日期 1981.08.04
申请号 US19800128362 申请日期 1980.03.07
申请人 PFIZER INC. 发明人 HOLLAND, GERALD F.
分类号 A61K31/38;C07D307/68;C07D333/38;(IPC1-7):A61K31/38;A61K31/34 主分类号 A61K31/38
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