发明名称 WHITENING COSMETIC
摘要 PURPOSE:A whitening cosmetic, useful for whitening and beautifying the skin and sunscreen, and containing a monoester obtained by reacting kojic acid with an aliphatic carboxylic acid as an active constitutent. CONSTITUTION:A whitening cosmetic containing a monoester obtained by esterifying a kojic acid solution in pyridine with an aliphatic carboxylic acid chloride, e.g. butyric, caprylic, linoleic or fumaric acid chloride, at room temperature. The content of the monoester is 0.01-10% in a base of the cosmetic. The monoester inhibits the activity of tyrosinase present in the human skin, has a suppressing action on melanization, a high stability to pH, light and heat, good storage stability and oil solubility without undesirable side effects on the human body.
申请公布号 JPS5679616(A) 申请公布日期 1981.06.30
申请号 JP19790158304 申请日期 1979.12.05
申请人 SANSHO SEIYAKU KK 发明人 NAGAI SUMIYOSHI
分类号 C07D309/40;A61K8/00;A61K8/49;A61Q19/02;C12N9/99 主分类号 C07D309/40
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