1-OXO-1H-PYRIMIDO(6,1-B)BENZTHIAZOLE DERIVATIVES

摘要

New l-oxo-lH-pyrimido6,1-b!benzthiazole derivatives and their process of preparation of formula (I) are provided wherein R1, R2, R3 and R4, which may be the same or different, are selected from the group consisting of hydrogen, halogen, hydroxyl, nitro, trifluoromethyl and straight-chain or branched-chain lower alkyl, alkoxy or alkylthio radicals, or R2 and R3 can together represent an alkylenedioxy radical, and X is a hydroxyl group or lower alkoxy or tetrazolyl-5-amino radical, and the pharmaceutically acceptable, pharmacologically compatible salts thereof, the new derivatives when administered parenterally or perorally display antiallergic action and are useful for combating allergic diseases, for example, allergic asthma, hay-fever and urticiria; further the new derivatives possess anti-oedematous and anti-inflammatory properties.