摘要 |
<p>The invention provides a process for obtaining and preserving stable bacterial variants arising from pathogenic or non-pathogenic bacteria, the said process comprising subjecting the bacteria, in an acellular medium, at the moment of scissiparity, to the action of an inducing agent, especially plasmolysis by osmotic shock, so as to do away with the cell wall, and culturing the variants obtained on an osmotically equilibrated acellular nutrient medium. The bacterial variants so obtained can be used for the preparation of vaccines and of reagents for sero-diagnostics and the identification of germs of atypical illnesses.</p> |