| 摘要 |
<p>Compounds of the formula <IMAGE> and <IMAGE> wherein A is phenyl, p-hydroxy-phenyl, 2-thienyl, 3-thienyl or 3,4-disubstituted phenyl, where the substituents, which may be identical to or different from each other, are each chlorine, hydroxyl or methoxy; R is -NH-Z-X; Z is straight or branched alkylene of 1 to 6 carbon atoms or cycloalkylene of 3 to 6 carbon atoms; X is cyano, hydroxyl, mercapto, aminocarbonyl, aminosulfonyl, <IMAGE> <IMAGE> +TR OR1, OCOR1, SR1, SOR1 or SO2R1; R1 is straight or branched alkyl of 1 to 4 carbon atoms or phenyl; R2 is hydrogen or alkyl of 1 to 4 carbon atoms; and R1 and R2, together with an adjacent nitrogen atom to which they are attached, form a 3- to 6-membered heterocyclic ring; and non-toxic, pharmacologically acceptable salts thereof formed with inorganic or organic bases.</p> |
