摘要 |
<p>HALOARYLMALONAMIDOOXACEPHALOSPORINS Antibacterial haloarylmalonamido-1-dethla-1-oxacephalosporins of the following formula: wherein Ar is , , , , or (in which Hal and Hal' each is halogen and RO is hydroxy or protected hydroxy); COA and COB each is carboxy or protected carboxy including a pharmaceutically acceptable salt group; and Het is 1-lower alkyl-5-tetrazolyl, 1,3,4-thiadiazol-2-yl or 5lower alkyl-1,3,4-thiadiazol-2-yl, a pharmaceutical or veterinary composition comprising the said haloarylmalonamido-1-dethia-1-oxacephalosporin and pharmaceutical carrier, and a method for treating or preventing human or veterinary infectious diseases comprising administering the said antibacterial compound.</p> |