| 摘要 |
<p>A pharmaceutical composition which comprises a compound of the formula II II wherein R1 and R2 can be an alkyl, alkenyl, phenylalkyl or phenylalkenyl group optionally inertly substituted by a halogen, OH, OR3, O.CO2R3, SR3, or a COR3 group wherein R3 is a hydrocarbon group of up to 8 carbon atoms and the group NR1R2 contains a total of not more than 16 carbon atoms and esters of compounds of formula II and acid addition salts thereof, said esters having the following formula IV and V IV V wherein R1 and R2 are as defined above and A is an alkyl group of 1 - 8 carbon atoms optionally substituted by halogen or a group of the formula OA4, OCOA4, SA4, SO2A wherein A4 is a hydrocarbon group of up to 6 carbon atoms; A2 is a hydrogen atom, an alkyl group of up to 4 carbon atoms or a phenyl group optionally substituted by halogen or by a group A5 or OA5 where A5 is an alkyl group of up to 6 carbon atoms; and A3 is a phenyl group optionally substituted by halogen or by a group A5 or OA5 where A5 is an alkyl group of up to 6 carbon atoms or being selected from the group of esters consisting of phthalidyl, acetoxymethyl, pivaloyloxyethyl, ?-acetoxyethyl, ethoxycarbonyloxymethyl, and ?-ethoxycarbonyloxyethyl and a penicillin or a cephalosporin and a pharmaceutical carrier therefor.</p> |
