发明名称 NIEUWE PYRIDINE- EN PYRIMIDINE-DERIVATEN MET ANTI- -ONTSTEKINGS- EN IMMUNOREGULERENDE WERKING, ALSMEDE FARMACEUTISCHE PREPARATEN DIE DEZE VERBINDINGEN BEVATTEN.
摘要 A series of 4-(2-hydroxyethylthiomethyl)pyridines and related compounds, and their pharmaceutically acceptable acid addition salts, having antiinflammatory and immunoregulatory activity are disclosed. Preferred compounds include 4-(2-hydroxyethylthiomethyl)pyridine itself, as well as 4-(2-hydroxyphenylthiomethyl)pyridine, 4-(2-hydroxy-1-propylthiomethyl)pyridine, 4-(3-hydroxy-2-butylthiomethyl)pyridine, 4-(2-hydroxyethylthiomethyl)pyrimidine, the acetate esters corresponding to the above compounds, and 4-(2,3-dihydroxy-1-propylthiomethyl)pyridine.
申请公布号 NL8005652(A) 申请公布日期 1981.04.21
申请号 NL19800005652 申请日期 1980.10.14
申请人 PFIZER INC. TE NEW YORK. 发明人
分类号 A61K31/44;A61K31/4409;A61K31/4418;A61K31/505;A61P29/00;A61P37/02;A61P37/06;C07D213/26;C07D213/28;C07D213/30;C07D213/32;C07D213/55;C07D213/65;C07D239/26 主分类号 A61K31/44
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