| 发明名称 |
METHOD FOR PRODUCING 6,7-DIMETHOXY-4-AMINO-2-(4-(2-FUROYL)-1-PIPERAZINYL)QUINAZOLINE HYDROCHLORIDE HAVING AN ANTIHYPERTENSIVE EFFECT |
| 摘要 |
An improved method is disclosed for producing antihypertensively active 6,7-dimethoxy-4-amino-2-[4-(2-furoyl)-1-piperazinyl] quinazoline hydrochloride, viz prazosine hydrochloride, by reacting methyl-N-(3,4-dimethoxy-6-cyano-phenyl)-[4-(2-furoyl)-1-piperazinyl]th ioformamidate with a large excess of ammonium chloride. |
| 申请公布号 |
ZA8000501(B) |
申请公布日期 |
1981.02.25 |
| 申请号 |
ZA19800000501 |
申请日期 |
1980.01.28 |
| 申请人 |
ORION YHTYMAE OY |
发明人 |
KAIRISALO P;HONKANEN E;KOIVISTO M;PIPPURI A;THALER H;TUOMI S |
| 分类号 |
C07D307/68;A61K;A61K31/34;A61K31/495;A61K31/496;A61K31/505;A61K31/517;A61P9/12;C07D;C07D239/84;C07D405/12;C07D405/14;C07D407/14 |
主分类号 |
C07D307/68 |
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