发明名称 (DI)-16-PHENOXY AND 16-SUBSTITUTED PHENOXY-9-KETO PROSTATRIENOIC ACID DERIVATIVES AND PROCESSES FOR THE PRODUCTION THEREOF
摘要 Novel 16-phenoxy and 16-(o, m or p)-substituted phenoxy derivatives of (dl)-9-keto-11 alpha ,15 alpha -dihydroxy-17,18,19,20-tetranorprosta-4,5,13-trans-trienoic acid, the pharmaceutically acceptable, non-toxic lower alkyl esters and salts thereof and processes for the production of such compounds. These compounds possess prostaglandin-like activities and thus are useful in the treatment of mammals where prostaglandins are indicated. They are particularly useful as inhibitors of gastric acid secretion; and as agents for the control of asthmatic attack, because of their bronchodilating activity.
申请公布号 ZA7903293(B) 申请公布日期 1981.02.25
申请号 ZA19790003293 申请日期 1979.07.03
申请人 SYNTEX INC 发明人 GARAY G;VAN HORN A;EDWARDS J
分类号 A61K31/23;A61K31/557;A61K31/5575;A61P1/04;A61P43/00;C07C67/00;C07C401/00;C07C405/00 主分类号 A61K31/23
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