发明名称 |
CYANOMETHYLPHENETHANOLAMINES |
摘要 |
<p>Preparation of cyanomethylphenethanolamines useful as adrenergic stimulants is described. Preferred compounds such as 2-hydroxy-5-¢1-hydroxy-2-¢(1,1-dimethyl-2-phenylethyl)amino!ethyl!-benzeneacetonitrile are selective beta-adrenergic stimulants having relatively greater potency on respiratory smooth muscle than on cardiac muscle. Such compounds are particularly valuable in the treatment of bronchial conditions.</p> |
申请公布号 |
CA1095525(A) |
申请公布日期 |
1981.02.10 |
申请号 |
CA19770276774 |
申请日期 |
1977.04.22 |
申请人 |
BRISTOL-MYERS COMPANY |
发明人 |
KREIGHBAUM, WILLIAM E.;MATIER, WILLIAM L.;ROTH, HERBERT R. |
分类号 |
A61K31/20;A61K;A61K31/05;A61K31/13;A61K31/135;A61K31/275;A61K31/295;A61K31/395;A61K31/40;A61K31/403;A61K31/404;A61K31/405;A61P9/00;A61P9/04;A61P9/08;A61P11/08;A61P27/02;A61P27/16;C07C;C07C67/00;C07C253/00;C07C255/43;C07C255/53;C07C255/59;C07D209/04;C07D209/12;C07D209/14;C07D209/18;C07D209/20;C07D209/40;(IPC1-7):07C121/80;07D209/12 |
主分类号 |
A61K31/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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