| 摘要 |
Racemic antipodes and acid additives of title compds. [I; R1=H, (CH2)nR4(n=1, 2; R4=H, cyano, benzoyl), COR5 (R5=H, lower alkoxy, benzoyl, CH2NH2, CH2NHCH2, CH(CH3)NHCH2C6H5); R2=H, CH3; R3=NHCOR6 (R6=H, CH3, CH3O, C2H5O, methylthio, ethylthio) were prepd. by the reaction of II and III(X=halogen, acyloxy, OH). Thus, 3-O2NC6H4CHO reacted with EtNO2 in PhMe to give 3-O2NC6H4CH:CNO2Me(m.p. 56-58≦̸C), which was hydrogenated first over Pd/C in pyridine, then over Raney Ni in MeOH to give 3-NH2C6H4CH2CHMeCH2. I were useful as symphotomimetic drugs(no data).
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