发明名称 |
Prepn. of psychotropic drug intermediates - from 3-nitro-4-amino:anisole by five-stage process to 2-methoxy-4-amino-5-alkyl sulphonyl:benzoic acids |
摘要 |
<p>Prepn. of 3-methoxy-4-amino-5- alkylsulphonylbenzoic acids of formula (I) by redn. of 3-nitro-4-alkylsulphonylanisole (A) (where R2 is 1-3C alkyl) to the 3-amino analogue (B), bromination of (B) to give 2-methoxy-4-amino-5alkyl -sulphonylbromobenzene (C), treating (C) with Cu2(CN2) to give 2-methoxy-4-amino-5 alkylsulphonylbenzonitrile (II) and hydrolysing. Cpd. (I) is as (II) with CN replaced by -CO2H. Cpds. A, B, C and (II) are new.</p> |
申请公布号 |
FR2460923(A1) |
申请公布日期 |
1981.01.30 |
申请号 |
FR19790017612 |
申请日期 |
1979.07.06 |
申请人 |
ILE DE FRANCE ETUDES SCIENTIFIQU |
发明人 |
JACQUES ACHER ET JEAN-CLAUDE MONIER |
分类号 |
C07C315/04;C07C317/36;C07C317/48;(IPC1-7):07C147/11 |
主分类号 |
C07C315/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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