发明名称 |
Ansamycin antibiotic |
摘要 |
A new subspecies of Streptomyces nigellus Prokop, designated Streptomyces nigellus Prokop subsp. africanus Huang subsp. nov. ATCC 31496, when propagated under aerobic conditions in aqueous nutrient media, produces a mixture of antibiotics. One of these antibiotics is the known macrolide antibiotic cirramycin A; the ansamycin antibiotic is an analogue of protostreptovaricin and the structure has been established as 21-hydroxy, 25-demethyl, 25-methylthioprotostreptovaricin I.
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申请公布号 |
US4247462(A) |
申请公布日期 |
1981.01.27 |
申请号 |
US19800109253 |
申请日期 |
1980.01.03 |
申请人 |
PFIZER INC. |
发明人 |
CELMER, WALTER D.;CULLEN, WALTER P.;OSCARSON, JOHN R.;HUANG, LIANG H.;SHIBAKAWA, RIICHIRO;TONE, JUNSUKE |
分类号 |
C07D225/04;C12P17/10;(IPC1-7):C07D491/08 |
主分类号 |
C07D225/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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