发明名称 METHOD OF PREPARATION OF 3-(3-CARBOXY-4- HYDROXYPHENYL)-4,5-DIHYDRO-2-PHENYLBENZ(E)INDOLE AND VALUABLE INTERMEDIATES RELATED THERETO
摘要 <p>This invention is directed to the preparation of a compound, which in one of its possible tautomeric forms, is represented by formula I I wherein R1 and R2 are the same or different and each represents alkyl of from 1 to 6 carbon atoms or, together with nitrogen atom to which they are attached, from the pyrrolidino or the piperidino ring, and X is bromine or chlorine, in which a napthalene compound of the formula wherein R1 and R2 are as defined above is reacted with a phenacyl halide. These compounds are useful intermediates in the preparation of pharmaceutical products having antiinflammatory and analgetic activity.</p>
申请公布号 CA1092126(A) 申请公布日期 1980.12.23
申请号 CA19800344310 申请日期 1980.01.24
申请人 HOECHST AKTIENGESELLSCHAFT 发明人 EFFLAND, RICHARD C.
分类号 C07D295/10;(IPC1-7):07C97/10;07D295/10 主分类号 C07D295/10
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