The present invention provides a method of inhibiting the enzymatic activity of a serine protease comprising contacting such protease with an inhibitory amount of a compound of formula (I), wherein Z is a serine protease binding moiety; and R1 is an optionally substituted alkyl, alkenyl, cycloalkyl or aryl group.
申请公布号
WO0009542(A1)
申请公布日期
2000.02.24
申请号
WO1998US17449
申请日期
1998.08.17
申请人
CORTECH, INC.;GYORKOS, ALBERT, C.;SPRUCE, LYLE, W.;LEIMER, AXEL, H.;CHERONIS, JOHN, C.
发明人
GYORKOS, ALBERT, C.;SPRUCE, LYLE, W.;LEIMER, AXEL, H.;CHERONIS, JOHN, C.
