Bis(nitrosoureido)-polyol derivatives

摘要

The invention relates to bis(nitrosoureido)-polyol derivatives of general formula I B1-A-B2 (I) wherein A stands for an open chain polyol comprising 4 to 6 carbon atoms or a six-membered cyclic polyol, and B1 and B2 being attached to two different carbon atoms of the chain A, are identical or different, and stand for a group of general formula II <IMAGE> (II) wherein X stands for a halogen atom and Y and Z stand for a hydrogen atom or a nitroso group, with the restriction, that in B1 and B2 Y and Z must be different. The above compounds possess valuable cytostatic activity.