PARTIALLY PROTECTED HUMAN INSULIN-A CHAIN AND PROCESS FOR ITS PREPARATION

摘要

Partially protected human insulin-A-chain suitable as intermediate for insulin synthesis and process for its manufacture by reacting the partially protected peptide fragment 6 to 26 of the insulin-A-chain with the peptide fragment 1 to 5 containing an N-terminal amino protective group capable of being split off by 5% strength trifluoroacetic acid in methylene chloride.