发明名称 CLEAR, WATER-MISCIBLE, LIQUID PHARMACEUTICAL VEHICLES AND COMPOSITIONS WHICH GEL AT BODY TEMPERATURE FOR DRUG DELIVERY TO MUCOUS MEMBRANES
摘要 <p>Pharmaceutical vehicles for delivery of pharmacologically active chemical materials to mucous membranes, as well as pharmaceutically active compositions containing such vehicles, are provided. The pharmaceutical vehicles are clear, water miscible, physiologically-acceptable, liquid compositions which gel to a thickened, non-flowing and adhering consistency at human body temperature. They are liquid at ambient room temperature and have a gel transition temperature in the range of from about 25.degree.C. to about 40.degree.C. Aqueous solutions of certain polyoxyethylene-polyoxypropylene condensates are suitable vehicles. Also provided are pharmaceutical compositions containing added pharmacologically active chemical material, i.e., a drug or medicament. A method of delivering the drug or medicament to a mucous membrane is also provided.</p>
申请公布号 CA1090252(A) 申请公布日期 1980.11.25
申请号 CA19760268988 申请日期 1976.12.31
申请人 FLOW PHARMACEUTICALS, INC. 发明人 KREZANOSKI, JOSEPH Z.
分类号 A61K9/06;A61K9/00;A61K9/08;A61K47/02;A61K47/10;A61K47/34;A61P27/02;(IPC1-7):61K31/74 主分类号 A61K9/06
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