| 摘要 |
<p>Purified human Le form interferon proteins are characterized and isolated by sodium dodecylsulphate polyacrylamide gradient electrophoresis as two major species of observed molecular weights 18400+- 200 Daltons and 20100+-200 Daltons and four minor species. Each individual pure interferon protein has antiviral and anticellular activity, and each of the two major species raises antibodies which neutralise the other species. The pure interferon proteins are prepared from solutions thereof containing impurities by antibody affinity chromatography optionally preceded by ligand affinity chromatography. Antibodies against the pure interferon proteins are useful in antibody affinity chromatography purification of crude interferon. </p> |
