发明名称 DERIVATIVES OF BENZAMIDE, METHOD OF THEIR PRODUCTION AND THEIR APPLICATION, PHARMACEUTICAL COMPOSITION AND METHOD FOR PROVISION OF INHIBITING ACTION IN RESPECT TO HDAC
摘要 FIELD: medicine. ^ SUBSTANCE: invention is related to compound of formula (I), (values of radicals are described in formula of invention) or its pharmaceutically acceptable salts, to methods of its production, pharmaceutical composition, which contains it. Application of invention is described for manufacturing of medicinal agent intended for provision of inhibiting action in respect to HDAC in warm-blooded animal, in production of agent used for treatment of malignant tumor. Method is also described for provision of inhibiting action in warm-blooded animal. ^ EFFECT: compounds have inhibiting activity in respect to HDAC. ^ 15 cl, 17 tbl, 24 ex
申请公布号 RU2376287(C2) 申请公布日期 2009.12.20
申请号 RU20040132844 申请日期 2003.04.02
申请人 ASTRAZENEKA AB 发明人 STOUKS EHLEJN SOFI EHLIZABET;ROBERTS KREJG ANTONI;UORING MAJKL DZHEJMS
分类号 C07D251/14;A61K31/341;A61K31/426;A61K31/427;A61K31/435;A61K31/4365;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4425;A61K31/444;A61K31/445;A61K31/4465;A61K31/452;A61K31/4525;A61K31/453;A61K31/454;A61K31/47;A61K31/4709;A61K31/4725;A61K31/495;A61K31/4965;A61K31/497;A61K31/505;A61K31/506;A61K31/519;A61K31/53;A61K31/5375;A61K31/5377;A61P7/06;A61P25/14;A61P35/00;A61P43/00;C07D211/14;C07D211/34;C07D213/56;C07D213/74;C07D215/12;C07D237/08;C07D239/26;C07D239/42;C07D241/12;C07D241/18;C07D241/20;C07D251/18;C07D277/20;C07D277/24;C07D277/30;C07D295/14;C07D295/155;C07D307/54;C07D401/04;C07D401/06;C07D401/12;C07D403/04;C07D403/12;C07D405/06;C07D407/06;C07D409/04;C07D413/04;C07D413/06;C07D417/06;C07D473/08;C07D487/04;C07D495/04 主分类号 C07D251/14
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