发明名称 |
ANTIBODIES AGAINST TNF-α AND USE THEREOF |
摘要 |
FIELD: biochemistry.SUBSTANCE: invention relates to biochemistry, particularly to an anti-TNF(tumour necrosis factor)-α antibody or anti-TNF-α-binding fragment antibody. Also disclosed is a pharmaceutical composition for treating pathologies and diseases associated with TNF-α, containing a therapeutically effective amount of said antibody or fragment thereof.EFFECT: invention provides effective treatment of TNF-α-mediated disease.15 cl, 6 dwg, 25 tbl, 2 ex |
申请公布号 |
RU2595379(C2) |
申请公布日期 |
2016.08.27 |
申请号 |
RU20110145428 |
申请日期 |
2010.04.16 |
申请人 |
AbbVie Biotherapeutics Inc |
发明人 |
HARDING Fiona A.;AKAMATSU Yoshiko;DUBRIDGE Robert B.;POWERS David B. |
分类号 |
C07K16/24;A61K39/395;A61P1/04;A61P1/06;A61P19/02;A61P19/04;A61P37/00;C12N15/13 |
主分类号 |
C07K16/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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