| 摘要 |
<p>Process for the preparation of 4,5,6,7-tetrahydro-thieno2,3-c!- and 3,2-c!pyridines This invention relates to a process for the preparation of 4,5,6,7-tetrahydro-thieno2,3-c!- and 3,2-c!pyridines having the formulae: (I) and (II) in which R1 is selected from hydrogen and halogen; R2 is selected from hydrogen and hydroxy; R3 and R4, which may be the same or different, are each selected from hydrogen, C1-6 alkyl, phenylalkyl having 1-6 carbon atoms in the alkyl moiety, and phenyl C1-6alkyl substituted on the phenyl nucleus with at least a substituent selected from halogen, C1-6 alkyl, C1-6 alkoxy, hydroxy, nitro, cyano and trifluoromethyl; and their acid addition salts. Said derivatives possess therapeutically useful anti-sludge, anti-thrombosis and blood-platelet aggregation inhibiting properties.</p> |
