New 25-hydroxy-24-oxocholestane derivatives and preparation thereof.

摘要

The novel 25-hydroxy-24-oxocholestane derivatives of this invention can easily be converted to 24,25-dihydroxycholecalciferol or 1α,24,25-trihydroxycholecalciferol which is known as useful for medicine controlling the calcium metabolism of warm-blooded animals. Moreover, 25-hydroxy-24-oxocholestane derivatives can be converted to novel 25-hydroxy-24- oxocholecalciferol expressed by the following formula
<Chemistry id="chema01" num="0001"><Image id="ia01" he="38" wi="48" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>and novel 1 α,25-dihydroxy-24-oxocholecalciferol of the formula