| 摘要 |
The invention is concerned with fractionation of proteins, in particular with fractionation of immunoglobulin containing solutions, such as blood plasma, by continuous flow electrophoresis. Hitherto, such solutions have been fractionated by ethanol precipitation methods (e.g. the Cohn Method). Such methods separate the IgG component of immunoglobulins but cannot separate the useful IgM component. In the invention, the solutions are fractionated by continuous flow electrophoresis at a pH of between 7 and 8.4 and an electrical conductivity of between 1 and 2 mScm-1, thereby giving rise to fractions containing particular combinations of immunoglobulin components (IgG, IgM, IgA, IgD and IgE) with potentially valuable properties. |
