TRIAMINO-ANDROSTANES AND A PROCESS FOR THE PREPARATION OF THE SAID COMPOUNDS

摘要

This invention relates to compounds of the general formula I wherein Ac is an alkylcarbonyl group containing 1 to 4 carbon atoms in the alkyl chain R is methylene or ? NR2 group - where R2 is a C1-3 alkyl, and all the three substituents R are of the same meaning n is 1 or 2 m is 1, 2, 3 or 4 and di-quaternary salts thereof of the general formula and tri-quaternary salts thereof of the general formula wherein Ac, R, n and m are given above R1 is C1-5 alkyl, or allyl and A is halogen, and pharmaceutically acceptable acid addition salts of the compounds of formula I. It also relates to a process for their preparation. The compounds of the invention exhibit a curone-like non-depolarizing neuromuscular-blocking effect.