| 摘要 |
Benzenesulfonyl ures and its salts(I; x = pyridyl, pyrimidinyl, quinolyl, benzothiazolyl, benzoxazolyl; R = C1-3 alkyl; R1 = C3-6 alkyl, C5-9 cycloalkenyl, cycloalkenyl, bicycloheptyl, bicycloheptenyl, adamantyl, benzyl), useful as hyperglycemic agent, were prepd. by oxidn. of benzenesulfinyl urea and benzenesulfenyl uresa. Thus, 3.4 g 4-(β-(N'-methyl-N'-pyridyl -ureidoethyl)-benzenesulfinic chloride and 1.7 g cyclohexyl urea were treaed at room temp. for 20 min in 20ml pyridine to give N-[4-(β-(N'-methyl-N'-pyridyl-ureidoethyl)-benzenesulfonyl urea.
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