| 摘要 |
A compound of the formula <IMAGE> (I) +TR <IMAGE> (II) wherein Q is CH2, C=O, CHOH or CHCH2OH; M is O or NR6; where R6 is hydrogen, or certain alkyl, aralkyl, acyl or carboalkoxy substituted alkyl groups; R1 is hydrogen, or certain alkanoyl or amino substituted alkanoyl groups; R4 and R5 are each hydrogen or alkyl having from 1 to 4 carbon atoms; Z is alkylene having from 1 to 9 carbon atoms or -(alk1)-X-(alk2)n- where (alk1) and (alk2) are certain alkylene groups and X is O, S, SO or SO2; W is a methyl, phenyl, substituted phenyl, pyridyl, piperidyl, cycloalkyl or substituted cycloalkyl group and the pharmaceutically acceptable and addition salts of said compounds having a basic nitrogen atoms. Said compounds are useful as analgesics and as intermediates therefore.
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