| 摘要 |
Process for the preparation of di-n-propyl acetonitrile of the formula : whereby, in a single step, sodium n-propylate in n-propanol medium is added to a reaction medium which is formed of a cyanacetate of general formula : in which R represents an alkyl radical having from l to 4 carbon atoms, and n-propyl bromide or iodide, the alkylation reaction taking place under reflux, the crude ester obtained is saponified with a 10 to 20 % solution of sodium hydroxide or potassium hydroxide, the resulting salt is acidified with a strong acid, to give crude di-n-propyl cyanacetic acid, which is decarboxylated by heating at a temperature between 140.degree.C and 190.degree.C, so as to obtain the di-n-propyl acetonitrile. |
