发明名称 |
Process for rosetting human B lymphocytes with Rhesus monkey erythrocyte |
摘要 |
Human peripheral blood lymphocytes are stimulated with either a polyclonal activator or an antigen which gives rise to immunologically activated B lymphocytes. These activated B lymphocytes are separated from non-activated B lymphocytes by relying on the fact that activated B lymphocytes possess a surface marker; the ability to rosette Rhesus monkey lymphocytes (RhMRBC), not found on their non-activated counterparts. Separation is achieved by rosetting with RhMRBC and subsequent density centrifugation of cells.
|
申请公布号 |
US4192917(A) |
申请公布日期 |
1980.03.11 |
申请号 |
US19790027307 |
申请日期 |
1979.04.05 |
申请人 |
MASSACHUSETTS GENERAL HOSPITAL, THE |
发明人 |
ZURAWSKI, VINCENT R JR |
分类号 |
C07K16/42;C12N5/0781;(IPC1-7):C12N7/04;A61K39/00 |
主分类号 |
C07K16/42 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|